Despite discussions on the topic, Sheldon Cooper does not have Asperger’s.

For a couple of times throughout the show, it was argued and established that Jim Parson’s character Sheldon Cooper has Asperger Syndrome, a type of autism that affects social skills. According to the writers, Cooper doesn’t have any disorders behind his difficulty in social interaction and nonverbal communication. That’s just the way his character is, or as they described it, “Sheldony.”